Probiotics for vaginal health: Help or hype?

Overwhelmed by probiotic promises? We cut through the noise to explain what the science actually says about probiotics for vaginal health, and where they could make a real difference.

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Probiotics for vaginal health: Help or hype?

Overwhelmed by probiotic promises? We cut through the noise to explain what the science actually says about probiotics for vaginal health, and where they could make a real difference.

Search “probiotics” online and you’ll be hit with thousands of products claiming to restore balance, prevent infections, and boost your health. From drinks and powders to capsules and vaginal tablets, the promises can feel endless (and overwhelming).

But with so much marketing and mixed messaging, how do you know what actually works? This article breaks down the science on probiotics for vaginal health: what they are, how they work, and whether they’re worth it. 

Spoiler: if you struggle with repeat vaginal infections, this one’s for you. 

What are probiotics?

Probiotics are live bacteria that, when taken in the right amounts, can support your health. They’re kept “live” through careful preservation (usually freeze-drying) so they stay active and work when you take them as supplements. Probiotics come in different forms: capsules, tablets, gels or suppositories, each designed to deliver the bacteria where they’re needed. 

For vaginal health, probiotics usually contain strains of Lactobacillus, the same bacteria that dominate a healthy vagina. These bacteria boost your vagina’s natural defences and help protect you from imbalance and infection. 

On product labels, you’ll see names like Lactobacillus rhamnosus GR-1, Lactobacullus reuteri RC-14 or Lactobacillus crispatus CTV-05. Each part of the name matters:

  • Genus (Lactobacillus): the broader bacterial group or “genus”.
  • Species (rhamnosus, reuteri, crispatus): the specific type within the genus, sharing core characteristics.
  • Strain code (GR-1, CTV-05): the subgroup of species, with tiny genetic differences. 

These extra details are important because not all probiotics work in the same way. Their benefits are strain-specific, meaning those tiny genetic differences make them work differently from each other. 

You’ll also see “CFU” on packaging, short for colony-forming units. This tells you how many live bacteria are in each dose. Effective probiotics usually contain billions of CFUs, but more doesn’t always mean better. The key is choosing the right strain at a clinically tested dose, usually a billion or more CFUs (shown as 108).

How do probiotics work?

When your natural Lactobacillus levels are strong, they act like a defence system for your vaginal microbiome. Probiotics support your natural Lactobacilli by:   

  • Keeping pH low: producing lactic acid to create a slightly acidic environment that makes it harder for harmful microbes and yeast to grow.

  • Producing antimicrobials: some strains release hydrogen peroxide and bacteriocins that directly damage or slow down pathogens.

  • Breaking down biofilms: preventing and disrupting the sticky layers that pathogens use to protect themselves from treatment.

  • Taking up space: attaching to the vaginal wall and blocking harmful microbes from sticking.

  • Working with your immune system: calming inflammation and strengthening your body’s own ability to fight infection.

Together, these actions help keep Lactobacilli in charge by maintaining a healthy state and reducing the risk of infections coming back. 

Do probiotics work for vaginal infections?

Probiotics aren’t a miracle cure. But the science shows they can support treatment and prevention of vaginal infections, especially when used consistently.

Bacterial Vaginosis (BV)

BV happens when protective Lactobacilli are outnumbered by other bacteria (like Gardnerella), causing odour, discharge, and discomfort. Antibiotics are the first-line treatment for BV, but adding probiotics makes them more effective. 

A 2024 review of 35 clinical trials found that women who combined probiotics alongside antibiotics had higher cure rates and were far less likely to see BV return. Using probiotics reduced recurrence by more than half in some cases. Vaginal suppositories, in particular, helped rebuild the microbiome. 

However, the way you administer probiotics is important. One trial in China found no added benefit of using oral probiotics for BV. Strains that successfully colonized when administered vaginally failed to work orally. This suggests that wider factors like delivery method, hormones, and even ethnicity matter when it comes to probiotics. 

Yeast infections (Vulvovaginal Candidiasis) 

Yeast infections are caused by an overgrowth of yeast called Candida, leading to itching, burning, and thick discharge. Probiotics aren’t a replacement for antifungal medication, but research shows they can play a supporting role. 

A recent review grouped probiotic use into three areas: 

  1. On their own: Results are mixed, with no clear evidence that they treat yeast infections effectively.

  2. Alongside antifungal treatments: Probiotics can speed up recovery and improve symptoms.

  3. For prevention: They show the strongest benefit, reducing repeat infections by up to 64%. 

Which probiotics are best for vaginal health?

Only a few strains have been tested in high-quality studies for vaginal health:

  • Lactobacillus rhamnosus GR-1 + L. reuteri RC-14: The most clinically studied pair, linked to restoring healthy bacteria and improving treatment results for BV and yeast infections. These can be found under different brand names like Vivag in Denmark or Ecovag in Sweden.

  • Lactobacillus crispatus CTV-05: Shown to lower BV recurrence thanks to its strong ability to produce lactic acid and keep the vaginal pH low. However, this strain is still under evaluation to get FDA approval.

  • Lactobacillus johnsonii: Studied for recurrent yeast infections, this strain has been shown to break down Candida biofilms and support immunity.

What should I look for in a probiotic?

If you’re considering trying probiotics for your vaginal health, here are a few tips:

  1. Choose strains tested specifically for vaginal health (e.g. L. crispatus CTV-05, L. rhamnosus GR-1, or L. reuteri RC-14).

  2. Check the CFU count. 1-10 Billion are needed to make an impact, anything less probably won’t make much difference.

  3. Think about delivery route: While oral probiotics may also support gut health, which is linked to vaginal balance, vaginal suppository probiotics work more directly and effectively.

  4. Use probiotics as part of treatment or prevention, not a replacement for antibiotics or antifungals.

Do I actually need probiotics?

Not everyone needs probiotics for their vaginal health. If infections are rare for you, they may not be necessary. 

But if you’re stuck in a frustrating cycle of BV or yeast infections that keep coming back, or occasionally experience symptoms, probiotics can be a valuable tool. The right strains can be a helpful addition to treatment and a proactive step to boost your resilience against repeat infections.

At UVISA, we believe preventative care is just as important as treatment. Supporting your vaginal microbiome (whether through lifestyle, medical care, or use of probiotics), is one of the most powerful ways to protect your long-term vaginal health. 

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